Screening

Set up, validate and carry out assays to evaluate efficacy and performance of compounds submitted by participants

SOURCES AND APPROACHES

  • Submissions
Participants submit candidate compounds for screening to OSDDm Screening Centers.

  • Screening
Screen compounds against 'go' and 'no-go' criteria

  • Microplate Assays
Adapt biochemical assays of parasite enzyme action, metabolism, and survival or proliferation to microplate format.

Establish Standard Operating Procedures and implement harmonized protocols at
OSDDm Screening Centers.

  • Discovery Pipeline
Make results available on-line for peer-review and democratic decisions on establishing the drug discovery pipeline.

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